Dr. Butt has a PhD from the University of Glasgow, UK, and trained as a Postdoctoral Fellow at the Georgetown University School of Medicine and a Staff Fellow at the National Institutes of Health, Bethesda, MD, before joining SmithKline Beckman (now GSK) Pharmaceuticals in 1982. He worked in several therapeutic areas during his 14 years in the SmithKline organization, where he led one of the first ubiquitin drug discovery efforts in the industry. Dr. Butt has an appointment as Adjunct Professor in Biomedical Engineering at Drexel University, Philadelphia and is active in a number of national and regional biotechnology organizations. He is a co-founder of Progenra, Inc.
Dr. Mattern has a PhD from Princeton University and received postdoctoral training as an NCI Fellow at the University of California San Francisco and subsequently worked at the NCI/NIH and at SB/GSK Pharmaceuticals in Oncology before joining Dr. Butt to establish Progenra Inc in November 2002. He was a member of the SB team that developed the anticancer drug Hycamtin/topotecan and, while at GSK, managed high throughput screening programs in several therapeutic areas. Dr. Mattern is a charter member of the DMP (drugs and molecular pharmacology) Study Section for the NCI and serves as an ad hoc reviewer on other study sections for academic and small business grants.