Our Science

Defining New Biology, the alliance of Mitochondria and Ubiquitin Proteosome System (UPS).

The Alliance That Powers Cellular Health

Mitochondria are the energy factories of the cell. UPS is the guardian of cellular health, removing toxic protein aggregates and damaged mitochondria to keep the cell on a path of healthy living.
Mitochondria are damaged in disease state and need UPS to fix the damage (mitophagy) as well as make new mitochondria (mitobiogenesis). The alliance between UPS and mitochondria is essential for healthy living.

Progenra is redefining a new era of medicine by empowering the mitochondria-UPS axis. Explore their role in neurodegenerative, cardiovascular, metabolic, and reversing the aging process.

Partnering illustration for Progenra
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Ubiquitin Proteasome System

Defining New Biology at the Intersection of Mitochondria and UPS

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Molecular Glues

Defining New Biology at the Intersection of Mitochondria and UPS

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Mitochondria and diseases

Exploring the powerhouse of the cell and its critical role in health and disease.

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Mitochondria and Aging

Understanding how cellular powerhouses shape the aging process and related diseases.

Partnership With Progenra

Driven by our powerful and highly productive drug discovery engine, we are delivering a pipeline of first-in-class therapeutics designed to transform the standard of care for patients.