Progenra receives funding from the Michael J Fox Foundation to develop Parkin activators to treat Parkinson’s disease.
May 2020. Progenra has received new funding for its Michael J. Fox Foundation Therapeutic Pipeline Award, Discovery and Development of Novel Parkin Activators. Progenra’s novel Parkin activator molecules are undergoing preclinical development, and this funding will support chemical optimization and other early preclinical activities necessary to advance the program to clinical trial for treatment of […]
Progenra Scientists publish a chapter in the ACS 2019 Medicinal Chemistry Reviews.
February 2020. Ubiquitin-specific proteases (USPs), the major class of deubiquitinating enzymes, or DUBs, remove conjugated ubiquitin from proteins in cells and in so doing help to regulate the content, location, or activity of the target protein. Approximately 80 USPs are expressed in humans, and many are linked genetically and biochemically with various diseases including cancer, […]
